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Scientists uncover role of protein critical for activating DNA replication

Scientists at Cold Spring Harbor Laboratory (CSHL) have discovered how a protein long known to be an essential activator of DNA replication actually triggers this process in cells.

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Researchers discover genetic differences between lethal and treatable forms...

A tumor's genetic profile is often useful when diagnosing and deciding on treatment for certain cancers, but inexplicably, genetically similar leukemias in different patients do not always respond well...

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Team cracks the atomic structure of a major cancer drug target

(PhysOrg.com) -- Researchers at the University of Helsinki, Finland, and the Paul Scherrer Institute (PSI) in Villigen, Switzerland, have determined the crystal structure of the ligand binding domain...

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Research team targets self-cannibalizing cancer cells

A team of scientists from Princeton University and The Cancer Institute of New Jersey has embarked on a major new project to unravel the secret lives of cancer cells that go dormant and...

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World first: Ovarian transplant helps woman be mum twice over

In what doctors described Wednesday as a world first, a Danish woman has given birth to two children after her fertility was restored using ovarian tissue that was removed, frozen, thawed and then...

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Nuclear physics promises earlier detection of brain tumors with just one scan

Time taken to detect brain tumours could soon be significantly reduced thanks to an ongoing pioneering project led by the University of Liverpool with the Nuclear Physics Group and Technology...

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Researchers find cancer-fighting properties in papaya tea

(PhysOrg.com) -- The humble papaya is gaining credibility in Western medicine for anticancer powers that folk cultures have recognized for generations.

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Computational feat speeds finding of genes to milliseconds instead of years

Like a magician who says, "Pick a card, any card," Stanford University computer scientist Debashis Sahoo, PhD, seemed to be offering some kind of trick when he asked researchers at the Stanford...

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Exploring the 'Davids and Goliaths' of therapeutic molecules

Two research units under Singapore's Agency for Science, Technology and Research (A*STAR), the Experimental Therapeutics Centre (ETC) and Singapore Immunology Network (SIgN), are collaborating with...

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Cancer drug effectiveness substantially advanced

Researchers have shown that a peptide (a chain of amino acids) called iRGD helps co-administered drugs penetrate deeply into tumor tissue. The peptide has been shown to substantially increase treatment...

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Temporary fix helps patients around drug allergy

(AP) -- Having a bad reaction to penicillin as a child doesn't guarantee you're still allergic decades later. And if the oncologist says you have to switch chemotherapies because of an allergic...

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Curcumin nanoparticles 'open up' resistant cancers

Pre-treatment with curcumin, a component of the spice turmeric, makes ovarian cancer cells more vulnerable to chemotherapy and radiotherapy. Researchers writing in BioMed Central's open access Journal...

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CXCR4: A new drug target in lung cancer

Lung cancer patients whose tumors over-express a cell surface molecule called CXCR4 do significantly worse than those who do not, Canadian researchers have found. Their work, reported at the 2nd...

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Transportation governed by simple rules

(PhysOrg.com) -- All life on earth is threatened by chaos. In this sense, a cell is like a ship which could at any moment sink in a sea of chaos. It must constantly consume energy to maintain the same...

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Viruses against cancer

Advanced gliomas regressed completely in rats after treatment with parvoviruses and the animals survived significantly longer than untreated animals. This was shown by scientists of the German Cancer...

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Plain to See: New contrast agents for magnetic resonance imaging of tumors

(PhysOrg.com) -- Magnetic resonance imaging (MRI) is primarily a medical imaging technique that is used to visualize different soft tissues within the body. In the field of cancer therapy, a contrast...

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New cancer guidelines: Exercise during and after treatment is now encouraged

Cancer patients who've been told to rest and avoid exercise can - and should - find ways to be physically active both during and after treatment, according to new national guidelines. Kathryn Schmitz,...

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Second-line CML drugs evoke faster, better front-line remissions

Two drugs approved for treatment of drug-resistant chronic myeloid leukemia provide patients with quicker, better responses as a first therapy than the existing front-line medication, according to two...

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Tumor virus is best predictor of throat cancer survival

The presence of human papilloma virus, the virus that causes cervical cancer, in tumors is the most important predictor of survival for people diagnosed with oropharyngeal cancer (cancer of the back of...

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Magnetic Nanoparticles Remove Ovarian Cancer Cells from the Abdominal Cavity

A major complicating factor in the treatment of ovarian cancer is that malignant cells are often shed into the patient’s abdominal cavity. These cells can then spread to other tissues, seeding new...

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